Menopause and melatonin

What is MENOPAUSE? Around age 45-50, oestrogen levels fall, and the menstrual flow becomes less or irregular and eventually stops. Menopause is the cessation of menses. But this does not mean that a woman has stopped making oestrogen. Her body still makes it from androstenedione in her fat cells, so it does not fall to zero. Progesterone, which is a major precursor of corticosteroids, falls close to zero instead. Without progesterone, the body increases another precursor hormone, dehydroepiandrosterone (DHEA), which produces other hormones like androstenedione, oestrogen and corticosteroid.

​Some scientists conducted a clinical study in perimenopausal women. Within just 6 months, melatonin was able to produce a total reversal of menopause and reconstitute a youthful cyclical-hormonal function, with all the beneficial consequences on a psychic and physical level. Melatonin, taken by women between 42 and 62 years of age, restored thyroid function, a silent and completely underestimated danger in women before and after the cessation of menstrual rhythm. Thyroid insufficiency that is not revealed by laboratory tests is probably at the root of many mental and somatic disorders in women in perimenopause and after the cessation of menstruation. Melatonin should be taken even before the onset of the first manifestations of menopause.

​References Pierpaoli, Walter. L'Uomo Senza Età. Morlacchi Editore, 2010.